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Syringe Filter

Syringe filters are single-use, membrane-based devices used for the removal of particulate impurities from liquid and gas samples prior to analysis by methods such as HPLC, ion chromatography, gas chromatography, ICP, and dissolution testing. Proper filtration of samples improves the quality and consistency of analytical results and decreases instrument downtime. Disposable syringe filters are commonly used for fast and efficient filtering.

Syringe filter specification

PVDF (Hydrophilic/Hydrophobic) syringe filters

Superior membrane quality for HPLC. Hydrophilic PVDF syringe filters do not require pre-wetting for use with aqueous samples. Hydrophobic PVDF filters require pre-wetting with an alcohol before use with aqueous samples.

• Low non-specific binding with exceptional chemical resistance

• Hydrophilic membrane provides excellent flow rates and low binding coefficients

• Certified for chromatographic performance

• Compatible with a wide range of aqueous and organic-based sample environments

• Recommended for HPLC and UHPLC  PVDF syringe filters have a well defined pore structure, giving effective retention of particles without excessive pore blockage. Compatible with aqueous and most organic solvents. They are excellent general filters for HPLC andorganic solvent sample clean up.

Application

HPLC and organic solvent sample preparation and clean up

Protein based samples with high non-specific binding

Environmental water samples

Specifications

Membrane:

HPLC certified PVDF(Hydrophilic/Hydrophobic)

Max. operating temperature:

<100 °C

Housing:

Medical grade, virgin polypropylene

Pore Size:

0.22 µm, 0.45 µm

Chemical Incompatibilities:

DMF, DMSO, MEK, acetone and most caustic solutions > 6N

 

Regenerated cellulose(RC) syringe filters

Superior chemical resistance, optimized for biological sample recoveries.

• Hydrophilic membrane provides excellent flow rates and extremely low binding coefficients

• Superior choice for biological assays, gel capsule dissolution testing, protein sample matrixes

• Compatible with a wide range of aqueous and organic-based sample environments

• Recommended for reverse phase and normal phase HPLC

Regenerated cellulose syringe filters are ideally suited for almost any laboratory procedure, from HPLC sample preparation to dissolution sample testing. Regenerated cellulose possesses superior chemical resistance in either aqueous or organic-based sample environments. Its extremely low biological-based binding coefficient is ideally suited for maximum sample recoveries of biological-based assays.

Regenerated cellulose contains no binders, surfactants or wetting agents to assure minimal extractables in analytical procedures.

Application

HPLC and organic solvent sample preparation and clean up

Dissolution sample analysis, especially high-binding tablets or capsules

Protein-based samples with high non- specific binding

Sample analysis which require maximum recoveries

Analysis requiring low non-specific binding over a wide pH range

Specifications

Membrane:

HPLC certified RC membrane

Max. operating temperature:

<100 °C

Housing:

Medical grade, virgin polypropylene

Pore Size:

0.22 µm, 0.45 µm

Chemical Incompatibilities:

Sulfuric acid, hydrochloric acid, phosphoric acid or nitric acid > 25%, DMF, phenol

 

Cellulose acetate syringe filters

For filtering of aqueous solutions or biological samples.

• Hydrophilic membrane provides excellent flow rates and extremely low protein-binding coefficients

• Superior choice for biological assays, gel capsule dissolution testing, protein sample matrixes

• Recommended for aqueous HPLC A physically strong membrane which can be used with heated liquids.

Applications

• Protein-based samples with high non-specific binding

• Sample analysis which require maximum recoveries

Specifications

Membrane:

HPLC certified Cellulose acetate

Max. operating temperature:

<100 °C

Housing:

Medical grade, virgin polypropylene

Pore Size:

0.22 µm, 0.45 µm

Chemical Incompatibilities:

Acids, NaOH, dichloromethane, chloroform,

ketones, DMSO, THF

 

Glass fiber (GF) syringe filters

• For large particulate removal.

• Increased sample throughput

• Low extraction neutral borosilicate glass

• For use with viscous or particle-laden samples GMF filters are available in a range of porosities.

Applications

• Clarification

• Pre-filtering of suspensions

Specifications

Membrane:

Binder free Glass fiber

Max. operating temperature:

<100 °C

Housing:

Medical grade, virgin polypropylene

Pore Size:

0.22 µm, 0.45 µm

Chemical Incompatibilities:

Limited resistance with ammonia, NaOH and KOH solutions

 

PTFE (Hydrophobic and Hydrophilic) syringe filters

• Excellent chemical resistance for use with organic matrices

• Excellent flow rates and high loading capacities

• Exceptional temperature stability

• Organic solvent recommended

• Hydrophilic PTFE can be used for the same application but no pre-wetting of the membrane is required

PTFE syringe filters are applicable for filtration of gaseous or organic solvent-based samples.Both membrane types exhibits broad chemical resistance and unsurpassed temperature stability to address aggressive sample matrixes and extreme temperature situations. The hydrophobic PTFE filter can be utilized as a moisture barrier in venting applications. PTFE hydrophobic membranes require pre-treatment with alcohol before being suitable for aqueous or high aqueous/organic samples. Do not use directly with aqueous solutions.

Applications

 HPLC and organic solvent sample preparation and clean up

 Dissolution sample analysis

General sample preparation prior to analytical analysis

Elevated temperature samples, caustic or acidic solutions

Specifications

Membrane:

PTFE (Hydrophobic and Hydrophilic)

Max. operating temperature:

<100 °C

Housing:

Medical grade, virgin polypropylene

Pore Size:

0.22 µm, 0.45 µm, 1.0µm....

Chemical Incompatibilities:

• Perchloric acid

• Methylene chloride (limited exposure)

• Dioxane, DMF, formic acid > 50%

• Aqueous-based sample matrix

(unless filter is pre-wetted with an alcohol

 

Nylon syringe filters

• Naturally hydrophilic with broad chemical resistance

• Excellent flow rates and high-throughput loading

• HPLC recommended

Hydrophillic nylon is extremely well suited for aqueous or organic sample preparation and HPLC, GC or dissolution sample analysis. Due to its excellent flow characteristics and mechanical stability, nylon offers the best combination of physical parameters to meet the most stringent analytical needs.

Applications

• HPLC and organic solvent sample preparation and clean up

• Dissolution sample analysis

• General sample preparation prior to analytical analysis

• Mixed sample matrix of aqueous or organic dissolved analytes

Specifications

Membrane:

HPLC certified nylon

Max. operating temperature:

<100 °C

Housing:

Medical grade, virgin polypropylene

Pore Size:

0.22 µm, 0.45 µm, 1.0µm....

Chemical Incompatibilities:

• Perchloric acid

• Methylene chloride (limited exposure)

• Dioxane, DMF, formic acid > 50%

• Aqueous-based sample matrix

(unless filter is pre-wetted with an alcohol

 

PES syringe filters — Ion chromatography (IC) certified

Precise results in sensitive analysis of ionic analytes.

• Certified for low-level IC interference by ICP analysis

• Hydrophilic membrane provides excellent flow rates and low binding coefficients

• Low affinity for binding drugs, ideal for dissolution testing procedures

This hydrophilic polymer has excellent cleanliness and is compatible with a wide range of solvents. It is the membrane of choice for ion chromatography applications.

Applications

• IC sample preparation and analysis

• Dissolution testing

Specifications

Membrane:

IC Certified PES

Max. operating temperature:

<100 °C

Housing:

Medical grade, virgin polypropylene

Pore Size:

0.22 µm, 0.45 µm

Chemical Incompatibilities:

• Protein-based samples in aqueous solutions

• Concentrated acids, chloromethane, chloroform, hexane, acetone, MEK, THF, DMSO